SPLS Tuesday Seminar - Disentangling organisms' metabolic responses and acclimation to environmental gradients through ecometabolomics

Dr. Malak Tfaily, Associate Professor, Environmental Science
University of Arizona
Tuesday, January 24, 2023 - 4:00pm
Marley 230 & Live on Zoom https://arizona.zoom.us/j/88614287572 Password: spls2023

Disentangling organisms’ metabolic responses and acclimation to environmental gradients through ecometabolomics
Advances in different -omics technologies have revolutionized biological research by enabling high-throughput monitoring of biological processes at the molecular level and their responses to environmental perturbation. Metabolomics is a fast-emerging technology in systems biology that aims to profile small compounds within a biological system that are often end products of complex biochemical cascades. Thus, metabolomics can enable discovery of the genetic basis of metabolic variation by linking the genotype to the phenotype. In this talk I plan to show how metabolomics and multi-omics can be integrated to understand the mechanisms by which environmental disturbances such drought, and increased temperatures impact organisms’ metabolic activity (plants and microbes) across multiple ecosystems.
Research interests in the Tfaily lab focuses on cutting edge metabolomics approaches which are then integrated with metagenomics, metaproteomics and metatranscriptomics to reveal how the genetic and metabolic features of organisms such as plants and microbial communities, and their biotic and abiotic interactions, give rise to ecosystem outputs in particular greenhouse gas (such as GHG are used as output of microbial respiration). My lab has been applying these approaches across multiple scales ranging from community scale characterization , to microcosms, to field chambers , all the way to landscape scale, and when coupled with disturbance studies, can better help us predict the stability of this system with further environmental changes. Due to the high diversity and complexity of metabolites, another focus of my research is the development of pipelines for enhanced metabolite annotation and identification as well as data analysis and visualization. These approaches are integrative and readily translatable across biomes, diverse ecological settings, and the agricultural/wildland interface.
Join us at 3:30 in the Marley lobby for refreshments.  
The presentation will begin at 4:00 p.m. in Marley 230
A live broadcast is available via zoom: https://arizona.zoom.us/j/88614287572  Password: spls2023