David Baltrus

Associate Professor - School of Plant Sciences
baltrus@arizona.edu, 821C Marley
520-626-8215 / 520-626-6573 (Lab)

Educational Background

  • Postdoc UNC Chapel Hill 2006-2010
  • Advisor: Jeff Dangl
  • PhD University of Oregon 2001-2006
  • Advisors: Karen Guillemin and Patrick Phillips
  • BA University of Delaware 1997-2001

Research Interests

  • Microbial Evolution: How do bacterial pathogens adapt and thrive in multiple environments?
  • Microbial Genomics: How and why do bacterial genomes change over time?
  • Microbial Genetics: What happens if we break this gene?

Selected Publications

Stice SP, Jan H-H, Chen H-C, Nwosu L, Shin GY, Weaver S, Coutinho T, Kvitko BH, Baltrus DA. 2023 "Pantailocins: phage-derived bacteriocins from Pantoea ananatis and Pantoea stewartii subsp. indologenes." Appl Environ Microbiol. 2023 Dec 21;89(12)
Weaver SL, Zhu L, Ravishankar S, Clark M, Baltrus DA. 2022 "Interspecies killing activity of Pseudomonas syringae tailocins." Microbiology (Reading). Nov;168(11).
Baltrus DA, Feng Q, Kvitko BH. 2022 "Genome Context Influences Evolutionary Flexibility of Nearly Identical Type III Effectors in Two Phytopathogenic Pseudomonads." Front Microbiol. 2022 Feb 18;13:826365.
Smith BA, Dougherty K, Clark M, Baltrus DA. 2022 "Experimental evolution of the megaplasmid pMPPla107 in Pseudomonas stutzeri enables identification of genes contributing to sensitivity to an inhibitory agent." Philos Trans R Soc Lond B Biol Sci. Jan 17;377(1842):20200474.
Baltrus DA, Clark M, Hockett KL, Mollico M, Smith C, Weaver S. 2022 "Prophylactic Application of Tailocins Prevents Infection by Pseudomonas syringae." Phytopathology. Mar;112(3):561-566.
Baltrus DA, Smith C, Derrick M, Leligdon C, Rosenthal Z, Mollico M, Moore A, Clark M. 2021 "Genomic Background Governs Opposing Responses to Nalidixic Acid upon Megaplasmid Acquisition in Pseudomonas." mSphere. Feb 17;6(1):e00008-21.
Smith BA, Leligdon C, Baltrus DA. 2019 "Just the Two of Us? A Family of Pseudomonas Megaplasmids Offers a Rare Glimpse into the Evolution of Large Mobile Elements." Genome Biol Evol. Apr 1;11(4):1192-1206.
Baltrus, DA. 2013 "Exploring the costs of horizontal gene transfer" Trends Ecol Evol 28(8): 489-95
Baltrus DA, Nishimura TM, Reinhardt JA, Romanchuk A, Chang JH, Mukhtar MS, Cherkis K, Roach J, Grant SR, Jones CD, Dangl JL “Dynamic evolution of pathogenicity revealed by sequencing and comparative genomics of 19 Pseudomonas syringae isolates” PLoS Pathogens 7(7):e1002132
Baltrus DA, Guillemin K, Phillips PC. 2008 "Natural transformation increases the rate of adaptation in the human pathogen Helicobacter pylori." Evolution. Jan;62(1):39-49.

Teaching Responsibilities

  • PLP 428/528 Lecture and Laboratory

Research Areas

  • Genomics, Bioinformatics, and Systems Biology
  • Microbiology
  • Plant Protection and Pathology